6 Comments
User's avatar
Johnny Savvy's avatar

Hello and thank-you for this post. Sorry about your Mom. Is that picture San Fran?

I never thought about my risk even though a relative had BC. I have a dude friend that got BC. His Mom had it. I read about ApoB/A1 ratio as an under-used indicator too- so maybe add that B to the test regimen?

When you ascribe reasons for the increase in cancer rates the discussion MUST include the "Dr. Day Tapes"! If you are not familiar-it is time. I have known of the Day tapes for 30+ years. Pretty much soured me on the entire manufactured reality that has been DESIGNED for us ie "modern" society.

Sage Hanna has many posts on the subject.

READ THIS and your life will not be the same!

http://www.sweetliberty.org/nobarbarians1.htm

Do you follow Dr Makis or 2nd Smartest Guy?

Did you see the book 'cancer is a parasite" or some such?

I think about the gov alcohol position that NO booze is healthy.

That might be from a physical standpoint,

but life without beer wouldn't be worth living!

Same with hot dogs.

They might kill you eventually, but boy o boy they sure hit the spot! ;-)

Everything in moderation...including moderation!

Also, vax status is now part of the big C equation, according the the good Dr. Dalgleish...

https://imahealth.substack.com/p/a-steam-train-coming-down-the-tracks?r=nvjqb&utm_campaign=post&utm_medium=web

Thank-you for all you do.

Sara Redondo, MD, MS's avatar

Dear Johnny,

Thank you for reading and for sharing about your friend. Male breast cancer is genuinely underdiagnosed, and the BRCA2 link in men is one of the most important things most people don't know. You're right to flag it.

On ApoB/A1 ratio, absolutely valid suggestion. I cover these extensively here: https://www.zenithwithin.com/p/apob-apoa1-ratio-heart-risk, and you're right that it belongs in a cancer metabolic monitoring discussion too. The metabolic-cancer connection runs deep.

On alcohol, I love that you're honest about it. For you, one beer may be a reasonable quality-of-life trade-off, that's a decision each person makes with their own risk profile in mind. My decision is different, for reasons specific to my family history and my genetics. Neither of us is wrong. The point is to make the decision consciously, with the data in front of you, rather than not knowing the data exists.

On the links and names, I try to stay anchored to peer-reviewed evidence, so I won't be heading down those roads. Not because I think all institutions are beyond question, but because the tools I use professionally require a particular kind of evidence standard to be useful.

The picture is from Madrid, that's where I'm from.

Thank you again for being here.

Warmly,

Sara

Jennifer Fouce's avatar

My mom is 66 with pancreatic cancer. She's stage 3 it's in her liver, chemo worked for months then stopped and June 2nd we learned it's growing bigger. So now we are trying a clinical trial. But my mom has no time- none of her genetic labs like the Brac genes or any genetics were there. My moms dad is 92 alive and great. Her mom died at 83 after kidney disease following a 15 year old heart transplant. So my mom

Really thought she'd live to 83. My mom smokes cigarettes and had to

Give up drinking beer and rum and cokes at the bar when she found out. I think smoking and drinking ( and not that much ) did this. If my mom knew that her stress/ her 2 bad habits greatly increase her life being cut short 20 years I think she'd had taken in more seriously. But my mom didn't know them combined really increase bad health .

Sara Redondo, MD, MS's avatar

Dear Jennifer,

I’m so sorry. Pancreatic cancer is devastating, especially when treatment stops working. Please don’t let this become blame. Smoking and alcohol can absolutely increase cancer risk, but cancer is usually caused by many overlapping factors, like genetics, inflammation, metabolism, exposures, immune function, and chance. The most practical thing now could be to ask her oncology team whether she has had germline genetic testing and tumor molecular profiling. In pancreatic cancer, these can sometimes reveal mutations that open the door to targeted treatments or clinical trials. And yes, you’re right. People deserve much clearer prevention conversations long before crisis.

Sending you and your family my very best wishes,

Sara

Jennifer Fouce's avatar

Yes thank you she is supposed to get a call Tomorrow about this trial but it's been a week in the making. She doesn't know how I feel about this cancer and her risk factors/ I'm sure my mom thought if it's sold at every gas station , pharmacy, and grocery store that it couldn't be that bad. Especially because cigarettes have warnings and drinking I don't think does? So I'm not blaming I told her I'd like to ask her dr- but he has signed off of chemo and idk If she will let me but I will try.

Sara Redondo, MD, MS's avatar

Yes, exactly. When something is sold everywhere, it sends the message that it must be relatively safe, and that is one of the biggest failures in public health communication.

For the trial call, you could simply ask: “Has she had germline genetic testing and tumor molecular profiling, and could either change her trial options?” Even if her chemo doctor has signed off, the trial team may still be able to guide that part.

I hope the call brings a real option for her.